Marvel's Spider-Man 2 could feature the death of Peter Parker, particularly
if the show decides to continue the Ultimate universe storyline of the comics.
The storyline in Brian Michael Bendis' 'Death of Spider-Man' (issue #160),
Peter fights his most formidable adversaries in one final fight to defend his friends and family.
Peter wins, but the battle takes its toll and he ultimately suffers from his injuries.
wish he had done the same thing for Ben, his uncle. Ben. Since Aunt May passed away in the movie Marvel's Spider-Man